产品货号：
Z27642
中文名称：
TAB2抗体
英文名称：
Anti-TAB2 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-TAB2 Antibody |
| 指标别名 | KIAA0733;MAP3K7IP2;TAB 2;TAB2;TAK1 binding protein 2 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | ELISA,IHC |
| 基因名称 | TAB2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | TAB2 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human TAB2.The immunogen is located within the last 50 amino acids of TAB2. |
| 计算分子量 | 76kDa |
| 成分 | TAB2 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | TAB2 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | TAB2 is an activator of MAP3K7/TAK1,which is required for for the IL-1 induced activation NF-kappaB and MAPK8/JNK.This protein forms a kinase complex with TRAF6,MAP3K7 and TAB1,thus serves as an adaptor linking MAP3K7 and TRAF6.This protein,TAB1,and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKL through the activation of the receptor activator of NF-kappaB (TNFRSF11A/RANK),which may regulate the development and function of osteoclasts.Recent experiments have shown that TAB2 and the related protein TAB3 constitutitvely interact with the autophagy mediator Beclin-1;upon induction of autophagy,these proteins dissociate from Beclin-1 and bind TAK1.Overexpression of TAB2 and TAB3 inhibit autophagy,while their depletion triggers it,suggesting that TAB2 and TAB3 act as a control point for autophagy. |
| Uniprot ID | Q9NYJ8 |
| 基因名全称 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 |
| 蛋白名全称 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 |
| 推荐稀释比 | TAB2 antibody can be used for detection of TAB2 by immunohistochemistry at 5μg/mL.Antibody validated:Immunohistochemistry in human samples.All other applications and species not yet tested. |
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